TYPES OF MALARIA: MALARIA RECRUDESCENCE

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 Case scenario:

                          A patient is treated for P.vivax with chloroquine. He felt well for the next 10 days, after which fever and shivering happened again. This time no parasites were seen on the smear. but you suspect malaria due to inadequate treatment.

An episode of malaria within 14 days of the previous episode can be due to improper treatment of malaria from the underdosing, wrong or sub-standard drugs, poor absorption, inadequate timing of treatment, or drug resistance. 

However, if a patient returns after 14 days then the first-line drug should be repeated since this represents possibly a new infection or relapse. Possibly, the drug concentration in blood was insufficient to suppress all parasites 

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